The Accelerating Excellence In Translational Science (AXIS)Charles Drew University of Medicine and Science

Round 8 (2018 - 2019)

Principal Investigator Project Title

1.  Cynthia Davis, PhD PrEP and PEP: Knowledge, Attitude, Beliefs and Behaviors (KABB) among at risk African American adults and youth

2.  Nestor Gonzalez-Cadavid, PhD EMT oncogenic induction or malignant stimulation of human breast epithelial cells.

3.  Piwen Wang, PhD Targeting cytidine metabolism in prostate cancer chemoprevention and treatment

4.  Seyung Chung, PhD Dual targeting cancer stem cells and telomerase for the treatment of colorectal cancer.

Round 7 (2017 - 2018)

Principal Investigator Project Title

1.   Eric Houston, PhD Cognitive training for ART adherence among African American and Latino YMSM.

2.   Mohammad Kamrul Hasan Role of CARF in nicotine plus a high fat diet induced metabolic and liver diseases

3.  Cynthia Gonzalez, PhD Watts Community Studio: A Community Health Assessment

4.  Jorge Espinoza-Derout, PhD Targeting Mitochondrial Dysfunction to Reduce Hepatic Steatosis Induced by Nicotine and High-fat diet

5.  Pranabanada Dutta, PhD Role of MCP-1 in cellular invasiveness in TNBC and its regulation by PARP1

Round 6 (2016 - 2017)

Principal Investigator Project Title

1.   Eva McGhee, PhD HPV and Health Disparities

2.   James Tsao, PhD Pharmacological modulation of ischemic muscle repair by stem cells in diabetes

Round 5 (2014 – 2015)

Principal Investigator Project Title

1.  Hamed Yazdanshenas, PhD Improving Aged Minorities Adherence to Medication by Mobile Health Technology (2Y)

2.  Kruttika Bhat, PhD Limiting GROa-induced triple negative breast cancer metastasis by PARP (2Y)

3.  Piwen Wang, PhD Enhanced chemoprevention by combining apigenin with green tea in

4.  Steve Chung, PhD Novel dual STAT3-telomerase targeting for colon cancer therapy (2Y)

5.  Yanyuan Wu, MD Association of IncRNA MALATI and breast cancer progression (2Y)

6.  Yong Wu, PhD Targeting metabolic stress and adaption: the combination of 2-Deoxyglucose and compound C synergistically induces breast cancer cell death (2Y)

Round 4 (2012 – 2013)

Principal Investigator Project Title

1.  Seyung Steven Chung, PhD Constitutively activated STAT3 induces pro-inflammatory IL-6 signaling and poor prognosis in HER2 overexpressing human breast cancer

2.  Silvana Constantinescu, PhD Cross-talk between adipose tissue and skeletal muscle

3.  Thomas Magee, PhD Metabolic Regulation of Programmed Nephrogenesis

Round 3 (2011 – 2012)

Principal Investigator Project Title

1.  Bita Amani, MHS, PhD Health Disparities Among Formerly Incarcerated Youth of Color in Los Angeles

2.  Homero del Pino, PhD Differences in Family Support for Alcohol Recovery between Younger and Older Gay Latino Men

3.  Satyesh K. Sinha, PhD Effect of M-CSF/GM-CSF Ratio on Macrophage Polarization in Diabetic Nephropathy

4.  Stanley H. Hsia, MD Exergaming in the Treatment of Adult Patients with Type 2 Diabetes Mellitus: Extension of Final Assessment

5.  Yanyuan Wu, MD, MSCR The Role of Maspin in Regulation of EMT and Inhibition of Tumorigenesis in HER2 Overexpressing Breast Tumors

Round 2 (2010 – 2011)

Principal Investigator Project Title

1.  I Jean Davis, PhD, PA, DC, MS The Effects of a Nutritional and Physical Activity Intervention in Licensed Child Care Centers in South Los Angeles

2.  Nestor Gonzalez-Cadavid, PhD Preclinical Proof of Concept for the Therapy of Diabetes-Related Critical Limb Ischemia with Muscle Derived Stem Cells Combined with Nitric Oxide Donors

3.  Paul Robinson, PhD Environmental Determinants of DASH Diet Adherence

4.  Suzanne Porszasz-Reisz, PhD Mighty Myostatin: Lean or Obese: Activating Signaling Pathway

Round 1 (2009 – 2010)

Principal Investigator Project Title

1.  Jorge N. Artaza, MS, PhD Vitamin D Stimulates Cardiac Differentiation and Ameliorates Fibrosis Associated with Cardiovascular Disease

2.  Matthew Ho, PhD, MD Reprogramming and Induction of Pluripotent Stem Cells for Treatment of Sickle Cell Disease

3.  Sheba George, PhD Evaluating the Acceptability of Cell Phone-Based Sexual Health Communication Among Young Men who Have Sex with Men (YMSM) in Los Angeles